Los 40 Principales is a Top 40 music radio network and radio station brand in many Spanish-speaking countries from PRISA Radio. Its origins started as a music show at Radio Madrid, today Cadena SER, in 1966, where the 40 Principales chart was born, and then evolved into a standalone radio station in 1979 at https://emisorasderadioonline.es/los-40-principales-en-directo/

The LOS40 radio network has a large number of listeners in Spain and in other Latin American countries, such as Argentina, Chile, Colombia, Costa Rica, Ecuador, Guatemala, Mexico, Panama, Paraguay and the Dominican Republic. Its mission is to lead the Top 40 format in all of the region, with a special focus on the Latin American market.

LOS40 is the largest radio network in Spain with more than 4 million listeners daily. The radio network belongs to the Spanish media company Prisa, which also owns five national radio music networks in Spain and one in Portugal.